The effectiveness of natri valproate in treatment of 238 children with grand mal seizure epilepsy at Hai Phong children hospital

Background:Seizure epilepsy is a social disease and appear at all age in most of countries. The rate of seizure epilepsy is increasing account for 10% of all cases.Objectives:This study aims to learn about the effectiveness of natri valproate in treatment of 238 children with grand mal seizure epilepsy at Hai Phong children hospital. Subjects and method: A retrospective and prospective study was conducted on 238 children with grandmal seizure epilepsy treated by natri valproate at Hai Phong Children Hospital from December 2005 to April 2007. Results:A complete remission rate was 87.8%, uncompleted remission in 10.1 % and non - responsive in 2.1 % after 15 days of treatment. After 6 months of treatment, a complete remission was seen in 92.5%, uncompleted remission in 6.1 % and non - responsive in 1.4% The electrocardiogram (ECG) showed paroxystic electric discharge in 71.9% of patients before treatment and in 32.1 % after treatment. Conclusion: In general, natri valproate was well tolerated in children. However, there were some complications and side effects such as somnolence and fatigue (23.6%), digestive disorder (5.7%), weight increase (4.7%), alopecia (2.8%), tremor (1.4%) but these complications and side effects were frequently mild and can be controlled.

Epidemiological characteristics of female sterilization clients at the Mother and Children Health Protection and Family Planing Center, Tay Ninh Province

This investigation involved 26 women who had sterilized at the Mother and Children Health Protection and Family Planing Center, Tay Ninh Province between February 1993 to February 1998. 86% of these clients aged from 25-39 years. Youngest clients were 21 years of age (2 women) and oldest were 45 years of age (3 women). Mean number of live births is 3.39+/-1.41 per one client, with more than 72% of the clients have had 3 live children or more. 81% of the clients are farmers and none of them are officials. Almost two thirds are illiteracy or have extremely low level of education. More than 37% of the clients reported that their income was less than 268,000 VND per month. 55% of the clients and 86% of their sex partners have not used any contraceptive method previously.

Treatment effect of herbal extract named HM2 on chronic cerebral circulated hypofunction

The acute toxicity (LD50) of herbal extract of HM2 was tested on white mice and the treatment effect of this herbal medication was investigated on 33 in-patients with chronic cerebral circulated hypofunction at Hµ T©y Hospital of Traditional Medicine. The results showed that HM2 was non-toxic in experimental animal at oral dose of 200g per kg. The adverse effect was not observed in clinical. This medication made no change in pulse, blood pressure, liver and renal function parameters as well as in hematological measurements. There was significant improvement in major symptoms.